内镜下双重色素法联合超声内镜对食管早期癌及癌前病变的诊断价值
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刘一品, 黄留业, 李延青
双重色素法; 超声内镜; 早期食管癌; 癌前病变刘一品,黄留业,李延青.内镜下双重色素法联合超声内镜对食管早期癌及癌前病变的诊断价值.世界华人消化杂志2005;13
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刘一品, 黄留业，烟台毓璜顶医院消化内科山东省烟台市 264000
李延青,山东大学齐鲁医院消化内科山东省济南市 250012
通讯作者：刘一品, 264000,山东省烟台市芝罘区毓璜顶东路20号,烟台毓璜顶医院消化内科. yipinliu@tom.com
电话：0535-6691999-82703 传真: 0535-6240341
收稿日期：2005-07-15 接受日期：2005-08-03
Evaluation ofdouble staining combined with endosonography in detection of earlyesophageal cancer and precancerous lesions
Yi-Pin Liu, Liu-Ye Huang, Yan-Qing Li
Yi-Pin Liu, Liu-Ye Huang, Department of Gastroenterology,Yuhuangding Hospital of Yantai, Yantai 264000, Shandong Province, China
Yan-Qing Li, Department of Gastroenterology, Qilu Hospital ofShandong University, Ji’nan 250012, Shandong Province, China
Correspondence to: Dr. Yi-Pin Liu, Departmentof Gastroenterology, Yuhuangding Hospital of Yantai, 20 Yuhuangding EastRoad, Zhifu District, Yantai 264000, Shandong Province, China.yipinliu@tom.com
Received: 2005-07-15 Accepted: 2005-08-03
Abstract
AIM: To investigate the effect of double staining, methylene blueand Lugol’s solution, combined with endosonography in the detection ofearly cancer and precancerous lesions of esophagus.
METHODS: Ninety-six patients with doubtful esophageal diseaseswere involved in this study. The lesions were firstly treated withmethylene blue (20 g/L) and then Lugol’s solution (30 g/L). Biopsieswere performed in the parts stained by methylene blue but unstained byLugol’s solution. Endosonography was also performed in the patientsdiagnosed with esophageal cancer, severe atypical hyperplasia, andBarrett’s esophagus.
RESULTS: Seven patients with esophagus cancer (including 2 casesof early cancer), 14 with atypical hyperplasia (7 light, 4 moderate, 3severe), 3 with Barrett’s esophagus, 8 with ulcer and 36 withinflammation. The total positive rate of double staining is 70.8%. Theaccuracy rate of endosonography is 92.3% (12/13) in detecting theinfiltration depth and the mediastinal lymph node metastasis of earlyesophageal cancer and precancerous lesions ......
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