摘 要：目的：探讨C反应蛋白(CRP)增高在心房颤动(房颤)发病中的意义。方法：应用免疫比浊法测定79例诊断为房颤患者血清CRP水平，与对照组比较，并对房颤按持续时间、病因不同分设亚组，进行统计学分析。结果：房颤组、对照组血清CRP水平分别为(4.30±2.87)、(1.15±0.90)mg/L，两组比较p<0.05。器质性、孤立性性房颤者CRP水平分别为(5.06±1.92)、(4.37±1.32)mg/L，均高于对照组，p<0.05。持续性、永久性房颤者CRP水平分别为(5.60±1.80)、(5.00±1.60)mg/L，均高于阵发性房颤(3.30±1.20)mg/L，p<0.05。结论：CRP增高反映的炎症状态可能促进房颤发生，以及呈持续发作。

    关键词：C反应蛋白； 心房颤动

    The Significance of Elevated C-reactive Protein in Patients With Atrial Fibrillation

    SHI Guo-ping， GAO You-lin

    (The Rugao People’s Hospital , Jiangsu Rugao 226500, China)

    Abstract：Objective：To evaluated the effect of CRP increasing in pathogenesis of atrial fibrillation. Method: The immunochemistry method was used to determine the serum CRP concentration in 79 AF patients . Grouping these patients according to the lasting paroxysm of AF and pathogenetic factor. Result : Serum CRP level of patients with AF (4.30±2.87)mg/L was higher than that in control group (1.15±0.90)mg/L,p<0.05 . The CRP level of isolated AF patients were (5.06±1.92) and(4.37±1.32)mg/L ,higher than that in control group respectively , p<0.05 . serum CRP level of persistant and permanent AF (3.30±1.20)mg/L ......