摘要：目的：探讨比较新生儿败血症感染途径、临床表现及病原学特点。方法：对78例新生儿败血症的临床资料、实验室检查及药敏试验进行分析。结果：①以皮肤、脐部、呼吸道为主要感染途径。②以体温异常(43.6%)， 少哭、少吃、少动(57.7%)，皮肤黄疸(66.7%)为主的临床表现。③致病菌以凝固酶阴性葡萄球菌、金黄色葡萄球菌、表皮葡萄球菌为主，共(87.2%)。④对青霉素、苯唑西林等耐药率为80%以上，对万古霉素耐药率为0%。结论：新生儿败血症临床表现不典型，治疗采用综合疗法根据血培养药效结果选择抗生素。注意新生儿脐部皮肤护理及呼吸道感染减少该病发生率。

    关键词：新生儿；败血症；病原菌

    Clinical Study on Neonatal Septicemia

    LI Na-sha,LIN Lin, LING Hua

    (Department of Pediatrics，the Second People's Hospital,Guangdong Shantou 515011,China)

    Abstract: Objective: To investigate the clinical characteristics of neonatal septicemia ,including the route of infection, clinical presentation and pathogenic bacteria .Method: Clinical data of 78 pediatric patients with septemia,including pathogenic bacterium, antibiotic sensitivity test and antibiotic use, were analysed retrospectivety. Results:The results showed that① the infection of the skin around umbilicus and respiratory tract are the main nfectiv routes ②the common presentations were abnormal temperature, poor feeding, irritability,and jaundice ③The results showed that solidifying enzyme negative taphylococcu and golden yellow staphylococcus were main pathogenic bacteria.87.2%.④Over 80% of them resisted penicillin and oxacillin and no one of them resisted vancomycin.Conclusion:It was suggested that nursing the skin around umbilicus and controlling respiratory infection should be payd attention or educe the attack of neonatal septicemia. ......