摘要:目的:应用三苯氧胺与光电离子治疗仪治疗乳腺增生病，比较两者的临床应用价值。方法:自2002年1月至2005年1月作者应用三苯氧胺与光电离子治疗仪治疗乳腺增生病各136例，比较两者在疗效、副作用以及停药后复发率等方面的差异。结果:疗效：三苯氧胺组(总有效率94.12%)优于光电离子治疗仪组(总有效率44.12%)(P<0.005)。副作用：三苯氧胺组副作用轻，发病率低，无须停药或特殊治疗。光电离子治疗仪组未发现有副作用。随访复发率：三苯氧胺组(14.71%)低于光电离子治疗仪组(88.46%)(P<0.005)。结论:三苯氧胺能消除乳房疼痛和肿块，疗效显著，副作用轻，发病率低，停药后复发率不高，仍是目前临床药物治疗乳腺增生病的首选用药。光电离子治疗仪能有效消除乳房疼痛且无副作用，主要适用于表现为乳痛症者。

    关键词:三苯氧胺; 光电离子治疗仪; 乳腺增生病; 治疗

    Clinical Study on the Treatment of Breast Hyperplasia by Tamoxifen and Light-electron-ion Therapeutic Machine

    CHEN Ye-xi, SHENG Wen-lv, MA Li-hua, et al

    (The Second Affiliated Hospital of the Medical College of Shantou University , Guangdong Shantou 515041, China)

    Abstract： Objective : To inquire into the clinic valuation of tamoxifen and the light-electron-ion therapeutic machine for breast hyperplasia. Method: The author used tamoxifen group in 136 cases and light-electron-ion therapeutic machine group in 136 cases. Additionally, comparision of the clinical effect and side effect and the rate of relapse was also studied. Results:① Clinical effect: The tamoxifen group was better than the light-electron-ion therapeutic machine group (P<0.005) ;② Side effect : The tamoxifen group had a low incidence of slight side effect, and it could not discontinue the drug or need special treatment. The light-electron-ion therapeutic machine group had none. ③Rate of relapse: the light-electron-ion therapeutic machine group was higher than the tamoxifen group (P<0.005). Conclusion: The light-electron-ion therapeutic machine can eliminate the patient’s pain so that it fits for the patients with breast pain. The tamoxifen can eliminate the patient’s pain and the lamps without severe side effect. Tamoxifen is the first chosen drug for breast hyperplasia at present. ......