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编号:10781905
氨茶碱用于腹腔镜全麻快速催醒临床观察
http://www.100md.com 《腹腔镜外科杂志》 2005年第4期
氨茶碱,,麻醉;氨茶碱;支气管痉挛,1资料与方法,2讨论,参考文献:
     【摘要】目的:总结氨茶碱用于全麻下行腹腔镜胆囊摘除术24 856例,术毕气管导管拔除前发生支管痉挛128例,氨茶碱治疗效果满意。方法:临床资料,男性51例,女性77例,23~86岁,体重48~108kg,一旦确诊为支气管痉挛,即刻停止对气道的直接刺激,保持患者安静同时静注AML(总量30~40mg/kg)和地塞米松5~10mg,纯氧通气提高吸入氧气浓度,清除呼吸道分泌物,痉挛症状缓解,哮鸣音,湿罗音消失。Paw≤20kPa,SPO2≥96%,呼吸平稳且心率、血压在正常范围。结果:氨茶碱用于全麻催醒及治疗支气管痉挛效果满意。结论:AML治疗全麻苏醒支气管痉挛有独特的优点,一方面,通过抑制细胞内磷酸二酯酶,使支气管平滑肌舒强,起到平喘作用,另一方面,有较强烈的兴奋呼吸,改善肺通气,拮抗吗啡类二氮卓类药引起的中枢抑制等作用,能显著改善和增强骨骼肌张力。

    【关键词】麻醉;氨茶碱;支气管痉挛

    The clinical summary about aminophy line appling for general stehesia recobery after laparoscopic cholecy stectomy during ten years.Armed police forces Xin Jiang general hospital LI Yunming,ZHUANG Shihua,LI Jie Urumq 830091,China

    【Abstract】Objective:To summarize anLinophylline appling for 128bronchial spasm cases during anaesthesia recovery in 24856 cases imdergpomg gemera;amaestjesoa of laparoscopic cholecystetomy.Methods: The electire laparoscopic cholecgstetomy,men 51 cases,women 77 cases,2386 years old,weight 48108kg.when the cases were diagnosised bronchial spasm,we mmediately stopped to stimulate their airway.intravenously injected minophylline(dose3040mg/kg).dexamethasonoe510mg and promoted oxygen oncentration.For a moment the symptom of bronchial spasm was remittenced,the asthma whistle and humid rale were disappeared,Paw≤20kPa,SPO2≥96% respiration kept in stable and heard rate.blood pressure kept in normal range.Results: Aminophylline applied for general anaesthesia recovery and treated the bronchial spasm,it's effection was satisfied.Conclusions: Aminophylline could restrain phosphodiestetrase to diastolic bronchial smooth muscle and calmed down asthma.In other hand,it also intentively could be exited respirtion,improved pulmonary ventilation,antagoned the central restrain of merphine and benzodiazepines,could obviously improved and enhanced the muscle tension. ......

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