摘要：目的：探讨甲氨喋呤(MTX)配合米非司酮不同给药方式治疗异位妊娠的疗效。方法：对136例异位妊娠患者随机分为MTX分次注射配合米非司酮(A组)；MTX单次注射配合米非司酮(B组)；单用米非司酮(C组)进行疗效比较。结果：A、B两组明显缩短血β-hCG降至正常范围的时间，减少住院日，提高治疗成功率(p<0.05)。结论：MTX分次给药和单次给药配合米非司酮治疗异位妊娠，疗效高，副作用少。尤其是分次MTX肌肉注射配合米非司酮疗效更优，临床上值的推广应用。

    关键词：异位妊娠；甲氨喋呤；米非司酮

    Comparison of Pharmacotherapy Which is Given in Different Ways in the Treatment of Ectopic Pregnancy

    GONG Li-ping，et al

    (Yishui Hospital of Linyi, Shandong Linyi 276400,China)

    Abstract: Objective: To evaluate the effectiveness of treatment in ectopic pregnancy by methotrexate(MTX) and mifepristone ,which is given in different ways.Method:136 cases were divided into group A,B and C.Group A was treated with MTX and mifepristone, MTX is given by many times,group B was treated with MTX and mifepristone ,MTX is given by one time,and group C was treated only with mifepristone. Result: Group A,B show great differences in shortening the time of blood β-hCG restoring to normal level, decreasing days in hospital,and raising cure rate than than of in group C(p<0.01) . Conclusion: The combination of MTX and mifepristone in traeting ectopic pregnancy is an effective method with highly successful rate and minor side effect. ......