阿昔洛韦纳米乳剂的制备
http://www.100md.com
| 第1页 |
| 第5页 |
参见附件(44KB，7页)。
段明华，王东凯，马淑飞
(沈阳药科大学药学院， 辽宁 沈阳 110016)
摘要： 目的 研究阿昔洛韦纳米乳剂的制备。方法 应用研磨-乳化法，单因素考察磷脂、大豆油、研磨温度、搅拌速度对处方的影响。结果 优化处方，制备了阿昔洛韦纳米乳剂。结论 制备阿昔洛韦纳米乳剂可改善阿昔洛韦水溶性差的特点，方法可行。
关键词：药剂学；纳米乳剂；研磨乳化法；阿昔洛韦
中图分类号：R943 文献标识码：A
Preparation of acyclovir nano-emulsion
DUAN Ming-hua,WANG Dong-kai,MA Shu-fei
(School of Pharmacy ,Shenyang Pharmaceutical University, Shenyang 110016, China)
Abstract: Objective To study the preparing method of acyclovir nano-emulsion. Method The method of trituration-emulsification was used to evaluate the effect of factors of the formulation, such as lecithin, glycerol, soybean oil, temperature of trituration, stirring rate. Result The formulation of acyclovir nano- emulsion was optimized. Conclusion The acyclovir nano-emulsion can improve the aqueous solubility of acyclovir and the method of preparation is feasible.
Key words: pharmaceutics; nano-emulsion; trituration-emulsification; acyclovir
您现在查看是摘要介绍页，详见PDF附件(44KB，7页)。