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电化学发光法检测胃癌患者血清标志物的临床意义
http://www.100md.com 《新疆医科大学学报》 2005年第7期
电化学,,胃癌;电化学发光;肿瘤标志物,1材料和方法,2结果,3讨论,参考文献:
     摘要: 目的:研究血清肿瘤标志物CA724、CA199与胃癌生物学行为的相关性及其临床意义。方法:采用电化学发光法检测53例胃癌患者术前、术后血清CA724、CA199水平,以20例胃炎患者(胃炎组)和40例正常人作为对照。结果:胃癌患者术后血清CA724、CA199水平较术前明显下降,与病理分型、临床分期呈正相关关系,但差异无统计学意义(P>0.05)。结论:提示血清CA724、CA199水平的变化与胃癌的恶性生物学行为有关。

    关键词:胃癌;电化学发光;肿瘤标志物

    Clinical signification of serum tumor marks of the gastric cancer deteted by electrochemical luminescence

    XU Yi, MU ChaoDong, JI Jun, et al

    (Department of Clinilal Labonitory, Affiliated Cancer Hospital, Xinjiang Medical University, Urumqi 830011, China)

    Abstract: Objective: To study the relationship between tumor marks (CA724,CA199) and the biology behavior of the gastric cancer. Methods: The serum value of CA724, CA199 of the 53 cases with gastric cancer were detected by electrochemical luminescence before and after the operation. At the same time, 20 cases with gastritis and 40 cases of the normal were checked by the same methods. Results: The preoperative serum values of CA724, CA199 were higher than that of postoperative. The serum values of A724, CA199 had closed relationships with the age, pathology classify, and clinic stages, but had no difference (P>0.05). Conclusion: It is suggested that the expression of CA724, CA199 has relationship with the biology behavior of the gastric cancer. ......

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