摘要:目的 探讨肝癌病人治疗前后血浆凝血酶调节蛋白(TM)、蛋白C(PC)抗原和D-二聚体(D-D)的临床意义。 方法 用ELISA法对25例肝癌病人治疗前、后血浆TM、PC抗原，用免疫比浊法对其D-D含量进行检测。 结果 肝癌病人Ⅰ、Ⅱ、Ⅲ期各指标差异均有显著性，自Ⅰ期到Ⅲ期，血浆TM、D-D逐渐升高，PC抗原逐渐降低。Ⅰ、Ⅱ期病人手术后PC进一步降低，D-D升高，TM下降，但Ⅱ期病人TM仍较对照组高。 结论 血浆TM、PC抗原、D-D含量可作为肝癌病情进展，疗效观察及预后的指标之一。

    关键词:肝癌;凝血酶调蛋白;蛋白C;D-二聚体

    Clinical significance in determination of plasma thrombomodulin protein C antigen and D-dimer in liver cancer pa-tients.DENG Rui-lian，LUO Bing-fen，KUANG Mu-zhu.(1.Shilong People's Hospital of Dongguan City，Dongguan523321，Guangdong，P.R.China)

    Abstract:Objective To study the clinical significance of plasma thrombomodulin(TM)，protein C(PC)antigen and D-dime(D-D)before and after treatment in liver cancer patients. Methods 25liver cancer patients were selected into the study，the levels of plasma thrombomodulin and protein C antigen were measured by ELISA，and D-D was tested by immunoturbidimetric method. Results There were differences among three periods(l ......