前列腺增生组织中EGF、TGFβ1和iNOS表达及其临床意义
EGF,,前列腺增生；EGF；TGFβ1；iNOS；原位凋亡,1材料与方法,2结果,3讨论,参考文献:
摘要: 目的：研究前列腺增生组织中EGF、TGFβ1和iNOS表达及其临床意义。方法：应用免疫组化SP法检测87例前列腺增生组织中EGF、TGFβ1和iNOS表达，并分析与临床化验指标和临床症状(前列腺液中白细胞计数、卵磷脂计数、尿频、尿痛和夜尿)的关系。结果：(1)87例前列腺增生组织中EGF、TGFβ1和iNOS表达的阳性检出率分别为63.2%(55/87)、47.1%(41/87)和56.3%(49/87)。(2)临床症状与EGF、TGFβ1、iNOS表达之间差异无统计学意义(P>0.05)。结论：(1)前列腺增生的发生发展与EGF、TGFβ1和iNOS表达有密切关系。(2)前列腺增生临床症状与EGF、TGFβ1、iNOS表达关系不密切。关键词：前列腺增生；EGF；TGFβ1；iNOS；原位凋亡
Study on the expression and clinical signification of EGF, TGFβ1 and iNOS in Prostatic Hyperplasia
PU Jiangbo， CHEN Xiao， Nijiati
(Xinjiang Jiayin Hospital，Urumqi 830000, China)
Abstract: Objective: To investigate the expression of EGF, TGFβ1 and iNOS in prostatic hyperplasia and the relationship between clinical sings and their expression. Method: Specimens from 87 cases with prostatic hyperplasia were examined for EGF, TGFβ1 and iNOS by immunohistochemisry. And the results were analysed with the clinical signs. Result: (1)The positive frequency of expression of EGF, TGFβ1 and iNOS of tissues in 87 cases with prostatic hyperplasia was 63.2%(55/87), 47.1%(41/87) and 56.3% (49/87) respectivelg. (2)There is no difference between clinical sings and the expression (P>0.05). Conclusion: (1)It is suggested that the pathogen and development of prostatic plasia has a closed relationship with the expression of EGF, TGFβ1 and iNOS in prostatic hyperplasia. (2)There is not a closed relationship between clinical sings and the expression. ......
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