摘要:目的 了解肺炎支原体(MP)感染儿童免疫功能与临床特点。 方法 用免疫学方法对117例发热、咳嗽、肺炎支原体IgM或IgG阳性患儿的免疫功能进行测定并分析其临床特征。 结果 支原体肺炎患儿血清CD 3 、CD 4 (51.63±5.74、33.05±4.28)较正常对照组(66.32±5.17、40.95±4.82)明显降低(P<0.05)，血清免疫球蛋白则与正常对照组比较差异无显著性。117例肺炎支原体感染的儿童中，间断性咳嗽咳痰98例，低热盗汗54例，腹泻39例，肾脏损害7例，肝脏损害16例，皮肤粘膜损害8例，关节疼痛5例，心电图异常改变11例，误诊为其它疾病91例。 结论 肺炎支原体感染儿童的细胞免疫功能下降，而体液免疫无明显改变。肺炎支原体感染儿童临床表现复复杂多样，应及时查血MP-IgM作出早期诊断，抗感染药物单用疗效差，应用大环内酯类药物合用头孢类疗效较好。

    关键词:支原体;肺炎;儿童

    Determination and clinical analysis of immune function of117infants infected with mycoplasma pneumoniae.

    PENG Yan-zhong，JIA Hong，DENG Jie，et al.

    (Beijing University Shenzhen Hospital，Shenzhen518036，Guangdong，P.R.China)

    Abstract:Objective To investigate the immune function and clinical feature of117child cases with Mycoplasma Pneumoniae. Methods Immune function of the117child cases with mycoplasma pneumoniae，IgM or IgG positive，fever，cough was deter-mined with immunologic approach and its clinical feature was observed and analyzed. Results The results showed the level of CD 3 ，CD 4 (51.63±5.74，33.05±4.28)in children with mycoplasma pneumoniae was obviously lower than that of the normal con-trol(66.32±5.17 ......