酒精_____酒精性脂肪肝；非酒精性脂肪肝；生化指标

酒精性脂肪肝与非酒精性脂肪肝患者生化指标的对比分析

http://www.100md.com 《新疆医科大学学报》 2005年第5期

酒精,,酒精性脂肪肝；非酒精性脂肪肝；生化指标,1对象与方法,2结果,3讨论,参考文献：

     摘要：目的：探讨酒精性脂肪肝与非酒精性脂肪肝特异性的鉴别指标，以指导临床诊断。方法：对38例酒精性脂肪肝患者及151例非酒精性脂肪肝患者的血清酶、血脂、尿酸、血糖、红细胞压积等指标进行测定及分析。结果：酒精性脂肪肝组谷草转氨酶(AST)、谷草转氨酶/谷丙转氨酶(AST/ ALT≥2)、γ谷氨酰转肽酶(GGT)、尿酸(UA)异常的百分数分别为73.7%、34.2%、47.4%、60.5%，非酒精性脂肪肝组分别为27.8%、14.6%、20.5%、35.1%，两组相比差异有统计学意义。结论：AST、AST/ ALT(≥2)、GGT、UA等指标可能是鉴别酒精性脂肪肝与非酒精性脂肪肝有效的临床辅助诊断指标。

    关键词：酒精性脂肪肝；非酒精性脂肪肝；生化指标

    Comparison of serum biochemicals between alcoholic fatty liver and nonalcoholic fatty liver

    LI Yuhua , YAO Hua, XU Feili, et al

    (Department of Occupational Health and Environmental Health, College of Public Health, Xinjiang Medical University, Urumqi 830054, China)

    Abstract: Objective: To find specific and sensitive indexes to differentiate nonalcoholic fatty liver disease(NAFLD) from alcoholic fatty liver disease(AFLD) for clinic diagnose. Method: 38 AFLD patients and 151 NAFLD patients were given Serum biochemicals determination and analysis . Result: The higher abnormalities of AST levels (73.7%), AST/ALT more than 2(34.2%), GGT levels (47.4%), UA levels (60.5%) were found in patients with AFLD than those with NAFLD (27.8%, 14.6%, 20.5%, 35.1% respectively). Conclusion: AST, AST/ALT, GGT, UA might be useful in differentiating NAFL from AFL. ......

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