当前位置: 首页 > 期刊 > 《中国体外循环杂志》 > 2005年第4期
编号:10793479
犬的体外循环模型建立和管理
http://www.100md.com 《中国体外循环杂志》 2005年第4期
动物模型,犬;体外循环;动物模型,1材料与方法,2结果,讨论,参考文献:
     摘要:目的 总结22条犬的体外循环实验模型建立和管理的经验。方法 健康杂种家犬22条,雄性12条,雌性10条。建立中低温阻断停跳和常温不阻断不停跳的体外循环模型。并于体外循环开始前及转流中,进行激活全血凝固时间(ACT)、血细胞压积(Hct)和血气监测。结果 转流过程中Hct、PaO2、PaCO2和BE均在正常范围。结论 建立一个正确的体外循环模型是该动物实验成功的必要因素。

    关键词:犬;体外循环;动物模型

    The Establishment and Management of a Dog Model used for Cardiopulmonary Bypass

    ZHAO Yun, HU Ke-jian, CHENG Yue, YANG Gai-sheng, ZHANG De-lin

    (Department of Cardiac Surgery, Zhongshan Hospital Fudan University, shanghai 200032)

    Abstract: OBJECTIVE To summary the establishment and management of 22 dogs using two model for cardiopulmonary bypass(CPB). METHODS 22 dogs (12 male , 10 female) were subject to two perfusion management models: moderate hypothermia and heart arrest & normothermia and beating heart. ACT, Hct and blood gas were measured continuously. RESULTS All results of determination were in normal range. CONCLUSION The use of the correct animal model is essential for successful dog experiments.

    Key words: Dog; cardiopulmonary bypass; animal model

    随着麻醉和体外循环技术的发展 ......

您现在查看是摘要页,全文长 5956 字符