【摘要】 目的 评价MRI液体征象在良、恶性椎体压缩骨折鉴别诊断中的价值。方法 回顾性分析150例椎体压缩骨折患者，其中良性椎体压缩骨折101例，恶性椎体压缩骨折49例。分析液体征象出现与骨折病因及压缩程度的关系(卡方检验)。良、恶性椎体压缩骨折的诊断依据为：穿刺活检，明确的影像发现，临床及MRI随访，有无明确肿瘤病史。结果 液体征象位于邻近骨折的终板处，信号强度于T2WI类似于脑脊液信号。良、恶性椎体压缩骨折出现液体征象分别为33%和7%，经卡方检验两组之间差异有非常显著性(χ2＝16，P<0.001)。组织学检查证实液体征象区为骨质坏死、水肿及纤维组织。在良性椎体压缩骨折中，因椎体压缩程度不同，液体征象出现率不同。结论 MRI液体征象可鉴别良、恶性椎体压缩骨折。

    【关键词】 脊柱;骨折;核磁共振;液体征象

    Benign and malignant vertebral compression fractures:fluid sign at MR imaging

    LIU Zhen-sheng,LI Cheng,TENG Gao-jun.

    Department of Radiology,The People′s First Hospital of Yangzhou City,Jiangsu 225001,China

    【Abstract】 Objective To evaluate the fluid sign in benign and malignant vertebral compression fractures at magnetic resonance(MR) imaging.Methods The study group comprised of 150 consecutive patients with benign vertebral compression fractures (n=101) and malignant vertebral compression fractures (n=49).The occurrence of the fluid sign was correlated with the cause and severity of the fracture(χ2 tests).The diagnosis was confirmed with biopsy,unequivocal imaging findings,follow-up MR imaging,clinical follow-up and definite tumour case history or not.χ2 tests were used to assess significance.Results In fractured vertebral bodies,the fluid sign was adjacent to the fractured end plates and exhibited signal intensity isointense to that of cerebrospinal fluid in T2WI.The occurrence of fluid sign in benign and malignant vertebral compression fractures is 33%and 7% respectively.Difference between two groups is statistically significant(χ2＝16 ......