【摘要】 目的 探讨奥曲肽、垂体后叶素及其联合治疗食管、胃底静脉曲张破裂出血的疗效。 方法 94例临床证实的肝硬化食管、胃底静脉曲张破裂出血的患者随机分为3组。垂体后叶素组34例，0.3u/min持续静滴;奥曲肽组32例，100μg静注后以25μg/h持续静滴;联合治疗组28例合用上述药物。3组均连续应用3天。 结果 垂体后叶素组、奥曲肽组及联合治疗组平均止血时间分别为38±26h、21±8h及15±10h。3组间比较差异均有显著性(P<0.05)，奥曲肽组、联合治疗组均优先于单用垂体后叶素组。 结论 奥曲肽治疗食管、胃底静脉曲张破裂出血疗效好、不良反应少。

    【关键词】 静脉曲张;出血;药物治疗

    Clinical study of octreotide and Pituitrin in the reatment of esophageal variceal haemorrhage

    GONG Xiu-wen.

    Shunyi District Hospital，Beijing101300，China

    【Abstract】 Objective To determine the efficacy of Octreotide and Pituitrin in the treatment of esphageal variceal haemorrhage.Methods 94case were randomly allocated into three groups.Patients in Pituitrin group(34cases)were given Pituitrin0.3u per minute for3days.Patients in Octreotide group(32cases)were given100μg intravenous-ly followed by25μg intravenously drip per hour for3days.Patients in group three(28cases)were given both of the above therapy.Results The mean bleeding-controlled time in three group were38±26 ......