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    High-tech and frontier science is an enternal topic, and creativity is the driving force of development

    CAO Er-cheng

    Tianjin Tianhe Hospital, Tianjin 300050, China

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    Relationship between blood biochemical indexes and types of deficiency or excess syndromes(虚实证型) of traditional Chinese medicine in cases with hyperlipidemia

    TANG Rong-de, LUO Zhi-hua, JIANG San-yuan, YANG Jin-song, LI Ying-shi, LIU She-yan, GUO Ai-qun.

    Xinhui Hospital of Traditional Chinese Medicine, Jiangmen 529100, Guangdong, China

    OBJECTIVE：To explore the changes of blood lipids, blood glucose(Glu), uric acid (UA) and C reactive protein (CRP) in cases with hyperlipidemia and their relationship to deficiency or excess syndrome in accord to the differentiation of symptoms and signs in traditional Chinese medicine (TCM). METHODS：Three hundred and fifty-three patients with hyperlipidemia were divided into deficiency syndrome (虚证), excess syndrome (实证), and deficiency-excess miscellaneous syndrome (虚实夹杂证) groups. The total cholesterol (TC), triglyceride (TG), low density lipoprotein-cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), Glu, UA and CRP in serum were determined and compared among patients with different syndromes and types in TCM. RESULTS：In three syndromes and types of TCM, the changes in TC, TG, LDL-C, HDL-C and CRP were greater in patients with excess syndrome and than those in patients with deficiency-excess miscellaneous syndrome and those in patients with deficiency syndrome. The change of Glu was greater in patients with deficiency syndrome than those in patients with deficiency-excess miscellaneous syndrome and than those in patients with excess syndrome. The change of UA was greater in patients with deficiency syndrome, middle in patients with excess syndrome, and mild in patients with deficiency-excess miscellaneous syndrome. The elevations of TC and TG were slight in deficiency syndrome and moderate in deficiency-excess miscellaneous syndrome, but serious in excess syndrome. CONCULSION： The seven indexes of this study are related to different syndromes and types of TCM in hyperlipidemia in different degree. The hyperlipidemia can be distinguished by deficiency syndrome, excess syndrome and deficiency-excess miscellaneous syndrome according to the changes of these indexes. ......