【摘要】 目的 研究维库溴铵复合阿曲库铵或复合潘库溴铵的时效。方法 15例择期手术病人。静注2倍ED95剂量的维库溴铵，阿曲库铵和1倍ED95剂量的维库溴铵复合1倍ED95剂量的阿曲库铵。观察各组的起效时间、无反应时间、T125%恢复时间、T190%恢复时间及恢复指数。结果 维库溴铵与阿曲库铵复合的起效时间不变，作用时间与恢复时间延长。结论 维库溴铵复合阿曲库铵协同作用明显。复合以后，平均动脉压和心率也无明显改变。

    【关键词】 维库溴铵；阿曲库铵；相互作用

    Neuromuscular interactions between vecuronium and atracurium

    ZHANG Xi，LING Bin，GONG Wei，et al.

    Shanghai First People's Hospital， Shanghai 200080，China

    【Abstract】 Objective To determine the neuromuscular blockade after vecuronium combined with atracurium.Methods 15 patients undergoing selective surgery. 2×ED95vecuronium， atracurium， 1×ED95vecuronium with 1×ED95atracurium were given to each group respectively. Onset time， no-response period，T125% recovery time， T190% recovery time and recovery index were measured.Results The effect duration of vecuronium-atracuronium and the recovery time had prolonged.Conclusion The combinations of vecuronium and atracurium were found to be synergism compared with the effects of each drug alone.

    【Key words】 vecuronium;atracurium;drug interaction

    现在已经知道 ......