大鼠降结肠上皮γ-氨基丁酸及谷氨酸脱羧酶的表达特征
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汪芳裕, Maemura Kentaro, 朱人敏
γ-氨基丁酸;谷氨酸脱羧酶;结肠上皮;大鼠,汪芳裕,朱人敏,MaemuraKentaro,WatanabeMasahito,HirataIchi
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汪芳裕, 朱人敏, 中国人民解放军南京军区南京总医院消化内科 江苏省南京市 210002
Maemura Kentaro, Watanabe Masahito, 大阪医科大学解剖学教研室 日本大阪 569-8686
Hirata Ichiro, Katsu Ken-ichi, 日本大阪医科大学第二内科学教研室日本大阪 569-8686
汪芳裕, 男, 1965-03-20生, 湖北麻城市人, 汉族, 2001年日本大阪医科大学博士, 副主任医师, 主要从事消化内科的基础和临床研究.
日中医学会笹川奖学金制度 (第22期) 和南京市留学回国人员科研活动择优资助课题, 宁人字No.2004-83
通讯作者: 汪芳裕, 210002, 江苏省南京市, 中国人民解放军南京军区南京总医院消化内科. wangf65@yahoo.com
电话: 025-80860020 传真: 025-80860119
收稿日期: 2005-10-25 接受日期: 2005-12-08
Characteristic expression of γ-aminobutyric acid and glutamic acid decarboxylase in epithelial cells of rat descending colon
Fang-Yu Wang, Kentaro Maemura, Ren-Min Zhu, Ichiro Hirata, Ken-ichi Katsu, Masahito Watanabe
Fang-Yu Wang, Ren-Min Zhu, Department of Gastroenterology, Nanjing General Hospital of Nanjing Military Command of Chinese PLA, Nanjing 210002, Jiangsu Province, China
Kentaro Maemura, Masahito Watanabe, Department of Anatomy, Osaka Medical College, Osaka 569-8686, Japan
Ichiro Hirata, Ken-ichi Katsu, Department of Gastroenterology, Osaka Medical College, Osaka 569-8686, Japan
Supported by Sasagawa Medical Research Fellowship (1999. 22nd) and the Fund for Returned Chinese Studying Abroad of Nanjing, No.2004-83
Correspondence to: Dr. Fang-Yu Wang, Department of Gastro-enterology, Nanjing General Hospital of Nanjing Military Command of Chinese PLA, Nanjing 210002, China. wangf65@yahoo.com
Received: 2005-10-25 Accepted: 2005-12-08
Abstract
AIM: To detect the expression of γ-aminobutyric acid (GABA) and glutamate decarboxylases (GADs) in the epithelial growth zones of rat descending colon, and to investigate their relations with cell differentiation and proliferation.
METHODS: Immunocytochemical expression of GABA and GADs in the epithelial cells of rat descending colon was investigated by immunofluorescent staining and confocal laser scanning techniques, and the goblet cells were further revealed by wheat-germ agglutinin (WGA) histochemistry ......
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