腹部外科脓毒症临床救治258例
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岳茂兴, 李成林, 李学彪, 刘志国, 杨鹤鸣,
脓毒症;死亡率;外科手术;综合救治;营养代谢支持,岳茂兴,李成林,李学彪,刘志国,杨鹤鸣,姜玉峰,张诗琳,通讯作者:,Clinicaltreatmentofsever
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岳茂兴, 李成林, 李学彪, 刘志国, 杨鹤鸣, 姜玉峰, 张诗琳, 中国人民解放军第306医院腹部外科中心 北京市 100101
总装备部卫生局重点科研课题资金资助项目, No. 9521086
通讯作者: 岳茂兴, 100101, 北京市朝阳区安翔北路九号, 中国人民解放军第306医院腹部外科中心. yuemx@ns.cetin.net.cn
电话: 010-66354546-0
收稿日期: 2005-09-10 接受日期: 2005-9-30
Clinical treatment of severe sepsis in abdominal surgery: an anlysis of 258 cases
Mao-Xing Yue, Cheng-Lin Li, Xue-Biao Li, Zhi-Guo Liu, He-Ming Yang, Yu-Feng Jiang, Shi-Lin Zhang
Mao-Xing Yue, Cheng-Lin Li, Xue-Biao Li, Zhi-Guo Liu, He-Ming Yang, Yu-Feng Jiang, Shi-Lin Zhang, Abdominal Surgical Center of the 306th Hospital of Chinese PLA, Beijing 100101, China
Supported by the Key Program Foundation of Public Health Bureau of the General Reserve Department of Chinese PLA, No.9521086
Correspondence to: Mao-Xing Yue, Abdominal Surgical Center of the 306th Hospital of Chinese PLA, 9 Anxiangbei Road, Chaoyang District, Beijing 100101, China. yuemx@ns.cetin.net.cn
Received: 2005-09-10 Accepted: 2005-09-30
Abstract
AIM: To explore a compositive treatment for reducing the mortality rate of the severe sepsis in abdominal surgery.
METHODS: While general treatment was performed, 14 concrete measures were carried out in accordance with the following factors: inflammatory mediator, bacteria, extoxin and endotoxin, dysfunction of microcirculation, immunity, nutrition, metabolism, basic diseases, and the function of organs. The combination of high dosage of anisodaminum and dexamethason was used in the short-term treatment. The nutrition support was used according to different stages of multiple organ dysfunction syndrome (MODS). Jiedu Guben Tang was orally administratered to regulate the imbalance of immunity and the inflammatory mediators.
RESULTS: A total of 30 patients were died in the 258 patients, and the mortality rate was 11.62%.
CONCLUSION: The new compositive treatment can significantly reduce the mortality of severe sepsis in abdominal surgery ......
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