关键词: 多发性硬化;磁共振成像;增强扫描;抑脂

    中图号:R466.1

    摘 要:目的 对照分析不同的扫描方法对多发性硬化(MS)患者的病灶显示程度，评价MR对MS的分期及预后的诊断价值. 方法 对24例临床确诊的MS患者行常规及增强MR扫描，4例采用抑脂(Fatsat)序列扫描，比较其对MS斑的显示率及范围，并与临床症状进行对照，以评价其诊断价值. 结果 24例患者中，T1WI显示MS斑16个，T2WI显示MS斑85个，12例增强扫描显示MS斑45个，4例采用Fatsat序列增强扫描显示病灶18个.T1WI显示MS斑为略低信号，T2WI显示MS斑为圆形或卵圆形高信号，见于皮层下白质内，增强扫描中，颅内病灶呈斑片状增强，脊髓病灶呈条索或片状增强，位于脊髓背及侧方，采用Fatsat序列扫描，MS斑呈斑块状增强，较T1WI及T2WI病灶大，边界清楚. 结论 T2WI对静止及活动期MS斑均能较好的显示，T1WI仅能部分显示静止期MS斑，增强扫描能较好显示活动期病灶，Fat-sat序列较SE序列能更好显示MS斑的形态.MS的临床症状尤其神经损害与MRI表现有较强的相关性.

    Research of MRI scan methods in multiple sclerosis

    YING Hong，HUANG Zhi-Lan，ZHANG Gui-Xiang，YOU Zhi-Jun，LIU Man-Sheng，ZHAO Hai-Tao

    Department of Radiodiagnosis，Xijing Hospital，Fourth Military Medical University，Xi'an710033，China

    Keywords:multiple sclerosis;MRI;Gd-DTPA enhancement;fat saturation

    Abstract:AIM To evaluate the diagnostic value of different MRI scan methods in multiple sclerosis.METHODS The plain and enhanced MRI scan was carried out in24clinical diagnosed multiple sclerosis，and Fatsat(fat saturation)sequence was used in some cases after enhancement，then the display rate of MS lesion in different methods was compared with the clinical features to evaluate the diagnostic value of different MRI scan methods.RESULTS In24cases ......