关键词: 骨质疏松症;颈椎病;扫描电镜

    摘 要:目的 对老年骨质疏松患者颈椎椎体骨小梁经制备行扫描电镜检查，观察骨小梁的骨吸收发生机制. 方法 收集8例因老年骨质疏松合并颈椎病而行颈前路椎体钻洞减压植骨手术老年患者(平均年龄55岁)的颈椎椎体，同年轻成年人的颈椎椎体骨小梁相比. 结果 老年骨质疏松患者的柱状骨小梁相继发生明显的骨吸收，表现为骨小梁的变细、穿孔.骨小梁间的空隙因此明显增大.高倍镜下，可见骨小梁上卵圆形、狭长卵圆形或梭形的吸收陷窝.陷窝的大小、深浅及内容物都不一致.陷窝四周原来具完整胶原纤维层的静止骨面也先后出现骨吸收.骨吸收过程中，无机盐可以先吸收，残剩粗糙不规则的胶原纤丝.骨形成现象较少见到，说明在老年骨质疏松患者骨转换处于负平衡状态. 结论 颈椎椎体骨小梁异常改建是以不断增多的吸收陷窝导致骨小梁穿孔、变细、吸收甚至消失完成的，是造成椎体变形的主要原因.

    Bone resorption of trabeculae in osteoporotic cervi┐cal vertebral associated with cervical spondylosis:A scanning electron microscopic study

    CONG Rui，WANG Quan-Ping，LI Xing-Kui，FENG Li-Ning，YUAN Hao-Qing，BAI Jian-Ping，SUN Yin-Zhong

    1 Institute of Orthopaedics of Chinese PLA，Xijing Hospital，2 Department of Aerospace Clinical Medicine，Faculty of Aerospace Medicine，Fourth Military Medical University，Xi'an710033，China

    Keywords:osteoporosis;cervical spondylosis;scaning elec-tron microscope

    Abstract:AIM To study bone resorption patterns in osteo-porotic cervical vertebral associated with cervical spondylosis by scanning electron microscopy.METHODS The trabecu-lae of cervical vertebral were collected from8cases of aged cervical spondylosis patients associated with osteoporosis at an average age of55years ......