中药肝炎平对 CCl4 诱导的肝纤维化大鼠TGFb1/S
http://www.100md.com
熊章鄂, 但自力, 唐望先, 严红梅
肝炎平;TGFb1,Smad信号通路;肝纤维化熊章鄂,但自力,唐望先,严红梅.中药肝炎平对CCl4诱导的肝纤维化大鼠TGFb1,Smad信号通路的影响.世界华人消化杂志2006;14(2)144-15
 |
| 第3页 |
 |
| 第1页 |
参见附件(1064KB，6页)。
熊章鄂, 但自力,华中科技大学同济医学院附属同济医院消化内科 湖北省武汉市 430030
唐望先,华中科技大学同济医学院附属同济医院肝病研究所 湖北省武汉市 430030
严红梅,武汉市第七人民医院肝病科湖北省武汉市 430071
熊章鄂,男, 1978-10-09生,湖北省宜昌市人,汉族, 2003年华中科技大学同济医学院附属同济医院消化内科硕士生,主要从事消化系统疾病的研究.
国家自然科学基金资助项目, No.30440088
通讯作者:但自力, 430030, 湖北省武汉市汉口解放大道1095号,华中科技大学同济医学院附属同济医院消化内科.danzili@msn.com
电话: 027-83663611
收稿日期: 2005-11-08 接受日期: 2005-11-24
Effects of traditional Chinese medicine Ganyanping on TGFb1/Smadsignaling pathway in carbon tetrachloride-induced hepatic fibrosis of rats
Zhang-E Xiong, Zi-Li Dan, Wang-XianTang,Hong-Mei Yan
Zhang-E Xiong, Zi-Li Dan,Department of Gastroenterology, Tongji HospitalAffiliated to Tongji Medical College, Huazhong University of Science andTechnology, Wuhan 430030, Hubei Province, China
Wang-Xian Tang,Institute of Liver Research, Tongji Hospital Affiliated to Tongji MedicalCollege, Huazhong University of Science and Technology, Wuhan 430030,Hubei Province, China
Hong-Mei Yan, Departmentof Hepatology, Wuhan Seventh People’s Hospital, Wuhan 430071, HubeiProvince, China
Supported by theNational Natural Science Foundation of China, No.30440088
Correspondence to: Zi-LiDan, Department of Gastroenterology, Tongji Hospital Affiliated to TongjiMedical College, Huazhong University of Science and Technology, Wuhan430030, Hubei Province, China. danzili@msn.com
Received: 2005-11-08 Accepted: 2005-11-24
Abstract
AIM:To study the effects of Ganyanping on the experimental hepatic fibrosis induced by carbon tetrachloride (CCl4) in rats, and to explore its anti-fibrotic molecular mechanism.
METHODS:Thirty-eight healthy Wistar rats were randomly divided into normal control (N), model control (A), and Ganyanping therapeutic group (B). The rats in group N was treated with normal saline by intragastrical irrigation, and those in group A and B were subcutaneous injected with CCl4 to establish hepatic fibrosis model ......
您现在查看是摘要介绍页，详见PDF附件(1064KB，6页)。