关键词: 神经再生;神经移植;动物，实验

    摘 要:目的 通过兔腓总神经不同时限预变性神经移植，从组织学、免疫组织细胞化学、电生理、超微结构等多方面对神经功能恢复进行探讨. 方法 家兔42只分为A，B，C，D，E，F，G7组:A，B，C，D，E，F组分别为预变性0，4，7，14，21和28d移植组，G组动物双侧腓总神经分别作新鲜神经移植和预变性神经移植. 结果 2wk预变性神经移植与新鲜神经移植相比可显著降低轴突再生起初延迟期(由3.04～0.04d)，提高神经生长速度(由1.73～2.59mm·d-1 )，促进N-MCV(由25.14～29.21m·s-1 )，增进轴突通过率(由81.2%～91%).组织学观察预变性2wk再生轴突比新鲜神经移植组成熟，髓鞘化程度高而且早. 结论 预变性2wk神经移植无论在质和量上均优于新鲜神经移植，其次是预变性1wk神经移植组.预变性4d和3wk也有增强神经再生的作用.

    Predegenerated nerve graftting speeds up nerve re┐generation:Animal experiment study

    LI Cun-Xiao LI Ren-Sheng YIN Qi

    1 Center of Orthopaedics Surgery of Chinese PLA，Tangdu Hospital，Fourth Military Medical Univer-sity，Xi'an710038，China，

    2 Department of Or-thopaedic Surgery，Xijing Hospital，Fourth Military Medical University

    Keywords:nerve graft;nerve regeneration;animals，labora-tory

    Abstract:AIM To explore the effect of predegenerated nerve grafting on nerve regeneration.METHODS We re-viewed nerve regeneration of different period predegenerated graftting through histological;immunocytochemical;electron micoscopic and electrophysiological studies.The rabbits were divided into7experimental groups for different periods(0 ......