关键词: 精神分裂症;病例对照研究;产科并发症

    摘 要:目的 探讨产科并发症与精神分裂症的关系. 方法 病例对照研究，单因素、多因素分析，并计算相对危险度和95%的可信限. 结果 单因素分析显示，孕期并发症(OR=4.63，95%CI=1.27～20.66)、生产并发症(OR=3.29，95%CI=1.06～11.29)达到统计学意义.性别分层分析，男性生产并发症发生率明显高于对照组.多因素分析，孕期营养差、孕期并发症与精神分裂症有密切的关系，OR(95%CI)分别为3.98(1.13～14.07)，4.93(1.44～16.86). 结论 精神分裂症的发生与孕期、生产期环境因素密切相关，孕期、生产期损伤者为精神分裂症的高危人群.

    A case┐control study for obstetric complications and schizophrenia

    YIN Shang-Jiong XU De-Zhong SHI Jian-Guo ZHANG Xi MEN Ke

    1 Department of Epidemiology，Faculty of Preventive Medicine，Fourth Military Medical University，Xi'an710033，China，

    2 Xi'an Mental Health Center，Xi'an710061，China，

    3 Department of Psychiatry，Third Employee Hospital，Xi'an710043，China

    Keywords:schizophrenia;case-control study;obstetric com-plications

    Abstract:AIM To investigate the relation between obstet-ric complications and schizophrenia.METHODS A case-control study was conducted to analyze the odds ratio and95%confidence interval for the history of obstetric complica-tions by univariate and multivariate analyses respectively.RESULTS Univariate analyses showed that two risk fac-tors ......