【摘要】 目的 探讨肿瘤相关物质(TSGF)在诊断肿瘤中的临床价值。方法 使用比色法检测122例患者(68例非肿瘤患者，54例肿瘤患者)和50例健康对照组的血清TSGF含量。结果 肿瘤组与非肿瘤组、健康对照组的阳性率差异有非常显著性(P<0.01)；治疗前、治疗无效及复发患者的血清TSGF水平均明显高于治疗显效组和对照组(P<0.05)；局部、远处复发患者之间差异有显著性。结论 TSGF可作为肿瘤标志物的筛选试验，对肿瘤治疗疗效及预后判断，尤其是监测复发转移有较高价值，可在临床诊断中推广应用。

    【关键词】 肿瘤；肿瘤相关物质(TSGF)

    Serum tumor supplied group of factors in patients with cancer

    ZHOU Yan.

    Shanghai Huangpu District Central Hospital,Shanghai 200002,China

    【Abstract】 Objective To investigate the clinical significance of serum tumor supplied group of factors(TSGF)in patients with cancer.Methods The TSGF level was detected by spectrophotometer in 50 healthy controls and 122 patients(68 non-tumor patients,54 tumor patients).Results The positive rate of TSGF in tumor patients was higher than in normal group and non-tumor group(P<0.01).The TSGF levels in initiated tumors,non-responders and relapsed tumors were profoundly higher than those in responders and controls respectively(P<0.05).Compared with local regionally recurrent tumors,the TSGF level was obviously elevated in patients with distant metastic cancers(P<0.01).Conclusion TSGF detection might be used as screening test for tumor diagnosis,assessing response to treatment and predicting prognosis,especially monitoring recurrence and metastases of cancer. ......