关键词: 提睾肌;内皮，血管;脱噬作用

    摘 要:目的 研究大鼠提睾肌神经损伤后血管内皮细胞的凋亡. 方法 以免疫组织化学SP法，对大鼠提睾肌神经损伤后的血管内皮细胞Bcl-2，Bax和p53表达进行研究. 结果 支配提睾肌的神经损伤后，Bcl-2，Bax和p53的表达均有增强，但Bax和p53的表达明显强于Bcl-2(P<0.01和P<0.05).神经损伤1wk后凋亡水平最高(与24h组比较P<0.01). 结论 大鼠提睾肌血管内皮细胞失去神经支配后可产生过度凋亡，并可能对微循环产生不利影响.

    Apoptosis of vascular endothelial cells following cremaster nerve injury of rats

    ZHAO Zuo-Qing，ZHANG Ling，LIU Fu-Lan

    Department of Experimental Surgery，Tangdu Hos-pital，Fourth Military Medical University，Xi'an710038，China

    Keywords:cremaster;endothelium，vascular;apoptosis

    Abstract:AIM To study the apoptosis of vascular endothe-lial cell with injured cremaster nerve of the rat.METHODS The expression of Bcl-2，Bax and p53in endothelial cells with injured cremaster nerve was investigated by means of immunohistochemical SP method.RESULTS The expres-sion of Bcl-2，Bax and p53in endothelial cell of injured cre-master merve increased obviously ......