【摘要】 目的 通过光学显微镜检查，研究糖尿病甲襞微循环早期病理改变。方法 采用国产医用光学仪器厂生产的WX-753型显微镜，检查部位，左手环指，甲襞皮肤滴1～2滴香柏油，滑润指甲提高透明度放大倍数为80倍观察显微镜的形态、动态指标。结果 73例(男45例，女28例)年龄24～61岁之间的糖尿病患者，Ⅰ期与Ⅱ期差异无显著性，符合早期网膜视病理改变。结论 糖尿病在Ⅲ、Ⅳ期视网膜病变加重，严重影响甲襞循环，甲襞测定反映出视网膜病变进展，为临床对症治疗提供了指导意义。

    【关键词】 糖尿病；视网膜病变；甲襞微循环

    【Abstract】 Objective To study pathological change of microcirculation of nail fold in diabetic through optical microscope.Methods Cedaroil dripped on digitus quartus manus of left hand in order to increase transparency.We observed microcirculation of nail fold through optical microscope (WX-753) whose enlargement factor was 80.Results There were 73 cases (45 males and 28 females) whose ages ranged from 24 to 61 years old.There were no significant difference between grade-1 and grade-2.Conclusion Retinopathy was aggravated and microcirculation of nail fold was effected badly at grade-3 and grade-4 of diabetes.Microcirculation of nail fold was consistent with retinopathy and provided the direction on clinical treatment. ......