【摘要】 目的 探讨晚期宫颈癌及膀胱癌大出血时经动脉介入化疗栓塞治疗的临床效果。方法 对37例晚期宫颈癌、膀胱癌急、慢性大出血行双侧髂内动脉栓塞术，术中经导管灌注化疗药。结果 37例中32例术后12h出血即明显减少，3～5天出血停止，追踪4～12个月无复发；5例止血效果不佳者均为宫颈癌盆腔脏器广泛转移，其中3例于2周后再次行栓塞手术成功，1例放弃治疗，1例于3周后死亡，35例(94.6%)患者除症状改善外,1个月后CT检查肿瘤范围明显缩小。结论 采用动脉灌注化疗及栓塞治疗晚期宫颈癌、膀胱癌大出血，安全显效。不良反应轻微，值得推广应用。

    【关键词】 膀胱癌；宫颈癌；大出血；栓塞治疗

    Transcatheter artery infusion chemotherapy and embolization for the treatment of bleeding in cervical carcinoma and bladder carcinoma

    LI He,LIU Xing-lin,LI Xue-liang,et al.

    Department of Radiology,Chuxiong People Hosptial,Chuxiong 675000,China

    【Abstract】 Objective To study the clinical effects of transcatheter artery infusion chemotherapy and embolization on heavy bleeding in cervical carcinoma and bladder carcinoma.Methods 16 cases of advanced bladder carcinoma and 21 female cases of advanced cervical carcinoma underwent transcatheter artery infusion chemotherapy and embolization to treat acute or chronic heavy bleeding.Clinical symptom of bleeding was observed.Results 32 of 37 cases underwent significant reduce in blood lose in 12 hours after operation,bleeding stopping in 3～5 postoperative days,and no relapse was observed during the follow-up of 4～12months.The other 5 cases presented little efficacy because of metastasis,while 2 cases underwent successful reembolization and 1 cases died 3 weeks later resulting from abandoning treatment.The sizes of tumor in 35 cases reduced greatly one month after operation.Conclusion The treatment of transcatheter artery chemotherapy and embolization is effective and safe for severe blood lose in cervical carcinoma and bladder carcinoma. ......