Serum total bile acid a good marker for infantile
The department of clinical laboratory, Beijing Children's Hospital, recently employed the detection of total bile acid (TBA) for the diagnosis of infantile hepatitis syndrome and discovered that the specificity, sensitivity and stability of tendency in numerical changes were all superior to the conventional liver function examinations, especially during the diagnosis and treatment of toxic hepatitis in children caused by cholestasis or infection and drugs; TBA could serve as an accurate and specific parameter of detection. The study provided much more reliable diagnostic data for a scientific clinical management.
The researchers compared fasting serum TBA with other parameters in 67 in-patients with hepatitis syndrome and 100 cases of non hepatobiliary disorders as controls during the same period of hospitalization. The results revealed that TBA exhibited close correlation with the parameters of the routine hepatic function tests performed conventionally (ALP, DBIL, g-GT,CHO, TBil, ALT, AST). The positive rate of TBA was as high as 89.5 %, which were remarkably higher than ALT, DBIL and CHO, with an increased range reached up to 8-9 folds over the normal limits., http://www.100md.com
The researchers compared fasting serum TBA with other parameters in 67 in-patients with hepatitis syndrome and 100 cases of non hepatobiliary disorders as controls during the same period of hospitalization. The results revealed that TBA exhibited close correlation with the parameters of the routine hepatic function tests performed conventionally (ALP, DBIL, g-GT,CHO, TBil, ALT, AST). The positive rate of TBA was as high as 89.5 %, which were remarkably higher than ALT, DBIL and CHO, with an increased range reached up to 8-9 folds over the normal limits., http://www.100md.com