Research on endemic diseases in China leads in the
Chinese medical research workers had made special achievements in scientific research of the endemic diseases and their results of study had stepped into the front row of the world. This was a conclusion recently obtained by the Chinese Prevention and Treatment Research Center of Endemic diseases after an analysis of the data of national endemic disease scientific research.
To continue with the Chinese proclamation to the world the staged destination of basic elimination of iodine deficiency in October 2000 which signified the Chinese scientific research of endemic disease plunging into the front row of the world, the scientific research on Kaschin-Beck disease and Keshan disease had also reached the advanced level into the global level. The main embodiments are as follows:
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The Chinese scholars had accurately described the state of illness, the distribution status in time and space, the special features of epidemics and formulated the five standards of " Criteria of diagnosis of Kaschin-Beck disease". The concept and parameters of evaluation of active disease region were established; the virulence factor and the mode of transmission (etiological chain) were confirmed that the ultra frequently aggregated T-2 toxin being the substance of etiological factor. The incidence of Kaschin-Beck disease was then under control by substitution of eating rice or the food from the non-endemic regions to break the route of transmission.
, 百拇医药
The formulation and issue of "Criteria of diagnosis of Keshan disease" provided strong scientific evidence for early detection, diagnosis, and treatment as well as prevention of the latent types changing into the chronic ones. In the early 60's intravenous injection of massive dose of vitamin C and sub-hibernation fluid replacement were used for the treatment of cardiogenic shock of acute Kaschin-Beck disease. The fatality rate of patients with acute and sub-acute types of the disease decreased from an average of 40% to below 20 %. long term oral administration of digitalis preparations and living instructions remarkably improved the survival rate of the patients of acute and sub-acute types and in some regions the survival rate reached 75%. In the field of preventive medicine, it was further proved that the individuals dwelling in the endemic areas assumed a status of selenium deficiency in the internal milieu, and the effects of decreasing mortality and improving outcome in newly encountered cases of the acute and sub-acute types were confirmed by oral administration of sodium selenite. In the mid term of the 1980s 4.07 million persons in the northern serious endemic regions persisted on the practice of SE prophylaxis, using sodium selenite as the prophylactic agent for a large population group; this initiation act in the world by the Chinese scholars was awarded with a prize from the International Association of Bio-inorganic Chemistry.
, 百拇医药
Endemic fluorosis. The endemic range, the distribution of the illness, the endemic behavior were basically checked up in a national scale and the distribution diagram was depicted; the animal model of drinking tea type fluorosis was reproduced. The pathological changes of the drinking tea type fluorosis was studied and proved that long term drinking "tea brick" with high content of fluorine might cause fluorosis. Additionally, gratifying results were obtained in the studies one pathogenesis of fluorosis, the influence of fluorine on fluoridation and anti-fluoridation of the human body, fluorine and the related elements, the effective de-fluorosis agents and the anti-fluorine agents as well as the study related to endemic arsenic poisoning., 百拇医药
To continue with the Chinese proclamation to the world the staged destination of basic elimination of iodine deficiency in October 2000 which signified the Chinese scientific research of endemic disease plunging into the front row of the world, the scientific research on Kaschin-Beck disease and Keshan disease had also reached the advanced level into the global level. The main embodiments are as follows:
, http://www.100md.com
The Chinese scholars had accurately described the state of illness, the distribution status in time and space, the special features of epidemics and formulated the five standards of " Criteria of diagnosis of Kaschin-Beck disease". The concept and parameters of evaluation of active disease region were established; the virulence factor and the mode of transmission (etiological chain) were confirmed that the ultra frequently aggregated T-2 toxin being the substance of etiological factor. The incidence of Kaschin-Beck disease was then under control by substitution of eating rice or the food from the non-endemic regions to break the route of transmission.
, 百拇医药
The formulation and issue of "Criteria of diagnosis of Keshan disease" provided strong scientific evidence for early detection, diagnosis, and treatment as well as prevention of the latent types changing into the chronic ones. In the early 60's intravenous injection of massive dose of vitamin C and sub-hibernation fluid replacement were used for the treatment of cardiogenic shock of acute Kaschin-Beck disease. The fatality rate of patients with acute and sub-acute types of the disease decreased from an average of 40% to below 20 %. long term oral administration of digitalis preparations and living instructions remarkably improved the survival rate of the patients of acute and sub-acute types and in some regions the survival rate reached 75%. In the field of preventive medicine, it was further proved that the individuals dwelling in the endemic areas assumed a status of selenium deficiency in the internal milieu, and the effects of decreasing mortality and improving outcome in newly encountered cases of the acute and sub-acute types were confirmed by oral administration of sodium selenite. In the mid term of the 1980s 4.07 million persons in the northern serious endemic regions persisted on the practice of SE prophylaxis, using sodium selenite as the prophylactic agent for a large population group; this initiation act in the world by the Chinese scholars was awarded with a prize from the International Association of Bio-inorganic Chemistry.
, 百拇医药
Endemic fluorosis. The endemic range, the distribution of the illness, the endemic behavior were basically checked up in a national scale and the distribution diagram was depicted; the animal model of drinking tea type fluorosis was reproduced. The pathological changes of the drinking tea type fluorosis was studied and proved that long term drinking "tea brick" with high content of fluorine might cause fluorosis. Additionally, gratifying results were obtained in the studies one pathogenesis of fluorosis, the influence of fluorine on fluoridation and anti-fluoridation of the human body, fluorine and the related elements, the effective de-fluorosis agents and the anti-fluorine agents as well as the study related to endemic arsenic poisoning., 百拇医药