慢性乙型肝炎患者血清脂质水平与病理分级分期的关系
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洪永孟, 朱幼芙, 吴爱华, 侯金林
慢性肝炎;血脂;病理分级分期,洪永孟,朱幼芙,吴爱华,侯金林,通讯作者:,Relationshipbetweenserumlipidlevelan
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洪永孟, 广东省阳江市人民医院感染内科 广东省阳江市 529500
朱幼芙, 吴爱华, 侯金林, 南方医科大学南方医院感染内科 广东省广州市 510515
通讯作者: 朱幼芙, 510515, 广东省广州市, 南方医院感染内科感染内科. zhuyf0118@163.com
电话: 020-61641960
收稿日期: 2005-11-15 接受日期: 2005-11-30
Relationship between serum lipid level and pathological grading and staging in chronic hepatitis B patients
Yong-Men Hong, You-Fu Zhu, Ai-Hua Wu, Jin-Lin Hou
Yong-Men Hong, Department of Infectious Diseases, People’s Hospital, Yangjiang 529500, Guangdong Province, China
You-Fu Zhu, Ai-Hua Wu, Jin-Lin Hou, Department of Infectious Diseases, Nanfang Hospital, Nanfang Medical University, Guangzhou 510515, Guangdong Province, China
Correspondence to: You-Fu Zhu, Department of Infectious Diseases, Nanfang Hospital, Nanfang Medical University, Guangzhou 510515, Guangdong Province,China. Zhuyf0118@163.com
Received: 2005-11-15Accepted: 2005-11-30
Abstract
AIM: To investigate the relationship between the severity of liver histology and serum lipid level in patients with chronic hepatitis B.
METHODS: The serum levels of total cholesterol (TC), triglycerides (TG), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), and low density lipoprotein-cholesterol (VLDL-C) was measured and compared in 130 chronic hepatitis B patients and 30 healthy controls with automatic biomedical analyzer.
RESULTS: The levels of serum lipid were decreased with the enhancement of histological inflammation grading and fibrosis staging, and they were significant ly different in patients with G3, G4 grades (for inflammation degree) and S4 stage (for fibrosis degree) than those in the controls (P < 0 ......
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