【摘要】 目的 比较盐酸丁洛地尔和七叶皂苷钠两种药物治疗急性脑梗死的成本-效果。方法 将88例脑梗死患者随机分为盐酸丁洛地尔组45例(A组)和七叶皂苷钠组43例(B组)，运用药物经济学原理对A、B两组进行成本-效果分析。结果 A、B组成本分别为1384.20元、815.04元(P<0.05)；有效率分别为77.78%、76.74%(P>0.05)；成本-效果比分别为17.79、10.62。结论 从临床疗效及医疗费用考虑，七叶皂苷钠优于盐酸丁洛地尔。

    【关键词】 急性脑梗死；盐酸丁洛地尔；七叶皂苷钠；成本-效果分析

    Cost-effectiveness of buflomedil hydrochloride and sodium aescinate in the treatment of acute cerebral infarction

    GONG Jian-ping，WEN Chao，HUANG Ze-liang.

    The Second People's Hospital of Huaihua City,Huaihua 418400, China

    【Abstract】 Objective Comparison of the cost-effectiveness between buflomedil hydrochloride and sodium aescinate in the treatment of acute cerebral infarction. Methods 88 cases of acute cerebral infarction were randomized into 2 groups:group A (45 cases) was treated with buflomedil hydrochloride;group B(43 cases) was treated with sodium aescinate. the cost-effectiveness of the two groups was analyzed according to the principles of the medicines economics.Results The cost of A group and B group is resputively 1384.2 yuan and 815.04 yuan (P<0.05);their efficieny is 77.78 percent and 76.74 percent separately effects (P>0.05);the ratio of cost-effectiveness is 17.79 and 10.62.Conclusion Sodium aescinate has priority over buflomedil hydrochloride in regard to the clinicl medical costs. ......