【摘要】 目的 探讨床边即时脑利钠肽检测对心功能的预测价值。方法 入选148例患者，包括非心衰患者38例和心衰患者110例，分别予以床边即时BNP检测和左室射血分数测定。结果 心衰组BNP水平明显高于非心衰组，两组差异有非常显著性(P<0.01)；心衰患者按NYHA心功能分级后比较，可以发现随着分级升高，BNP水平不断升高，而LVEF不断下降，且各组间差异均有显著性；心衰组中36例患者抗心衰治疗前后BNP水平，结果发现治疗后血浆BNP水平明显下降(704±251ng/ml versus 468±151ng/ml，P<0.01)，简单相关分析提示：BNP与LVEF呈负相关(r＝-0.887，P<0.01)，BNP与年龄呈正相关(r＝0.181，P＝0.027)。结论 床边即时BNP不仅具有预测心功能价值，还可以作为判断心衰治疗效果的指标。

    【关键词】 脑利纳肽； 充血性心力衰竭； 心功能

    Rapid bedside test for brain natriuretic peptide predicts cardiac function

    DING yue-you，REN Jian-ying，GU Yi-min，et al.

    Department of Cardiology，Xuhui District Central Hospital，Shanghai 200031，China

    【Abstract】 Objective To investigate the predictive value of rapid bedside test for brain natriuretic peptide(BNP) to cardiac function. Methods We enrolled 148 cases including 110 congestive heart failure(CHF) and 38 non-CHF. Rapid bedside test for brain natriuretic peptide and left ventricular ejection fraction(LVEF) were measured in all selected patients. Results The plasma BNP levels in CHF patients is significant higher than that of non-CHF. According to the NYHA cardiac function classification ......