【摘要】 目的 探讨外科院内感染中的中心静脉导管相关性脓毒症(CRS)的发病因素和机制，并提出治疗和预防措施。方法 回顾性分析98例患者的临床资料。结果 CRS主要致病菌为表皮葡萄球菌、金黄色葡萄球菌和真菌，中心静脉导管(CVC)留置时间与CRS的发生率明显相关。结论 细致的导管护理，缩短导管留置时间(<14天)和准确使用抗生素是预防CRS的重要措施。

    【关键词】 中心静脉导管相关性脓毒症；致病菌；治疗

    Analysis of central venous catheter-related nosocomial infectious disease in surgery

    HUANG Tao，AiKeReMu，WO Jian-hua.

    Department of Surgery，Shanghai Xu Hui Center Hospital，Shanghai 200031，China

    【Abstract】 Objective To investigate the pathogenesis of central venous catheter-related sepsis the nosocomial infectious disease in surgery and propose the strategies for treatment and prevention. Methods 98 cases were reviewed. Results Staphylococcus epidermidis、Staphylococcus aureus and fungus were the major pathogens. Duration of catheterization correlated with definite CRS.Conclusion It can prevent central venous catheter-related sepsis to nurse central venous catheter carefully，to decrease the duration of catheter insertion(<14 days) and to apply antibiotics correctly.

    【Key words】 central venous catheter-related sepsis; pathogen;treat ment ......