Effects of severing vagus nerve and depressor nerve on cardiovascular function in firearm thoracic wound

    TAO Dengª²Shun, LIU Weiª²Yong, CAI Jianª²Hui, LI Hong, LI Tongª²Xun, GUO Jianª²Jun, AN Shuª²Jie

    1Department of Cardiac Surgery, General Hospital, Shenyang Military Command, Shenyang 110016, China, 2Center of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi¬ðan 710033, China

    ¡¾Abstract¡¿ AIM: To make clear instantaneous and incipient cardiovascular effects of firearm thoracic wound. METHODS: Eighteen rabbits were randomly divided into 3 groups, A: Model group; B: Severing of vagus nerve; C: Severing of depressor nerve. Animals were ligated the number 6ª²8 intercostal artery before wound. We severed the double vagus nerve in group B, and depressor nerve in group C. The animals was wounded in the same way of part one. The artery pressure, vein pressure, heart rate, LVSP and ¡Àdp/dtmax were monitored continuously. RESULTS: In group A, the artery pressure ascended immediately after wound, amount to 1.47¡À0.09 times of normal; then descended to 0.48¡À0.06 times of normal and stabled. The heart rate descended immediately and recovered slowly. The LVSP and heart rate descended immediately, but recovered very slowly. The changes of artery pressure inª²group B and C was smaller, and there were not obviously changes of heart rates. CONCLUSION: Blood pressure descends, heart rate is slow, myocardium withholds and LVSP descends in a few seconds after wound. They are related to the reflection of vagus nerve. It can block and relieve forenamed variety by disbranching vagus nerve and depressor nerve. ......