Changing of learning ability in rats during ischemic convalescence induced by sustained +Gz exposure

    CAO Xinª²Sheng, WU Xingª²Yu, SUN Xiª²Qing, LIU Tingª²Song

    Department of Aerospace Biodynamics, School of Aviation Aerospace Medicine, Fourth Military Medical University, Xi¡¯an 710033, China

    ¡¾Abstract¡¿ AIM: To investigate the changes of learning ability in rats during ischemic convalescence induced by sustained positive acceleration (+Gz) exposures. METHODS: Twentyª²four male SD rats were randomly divided into 3 groups: control group (C), +6 Gz/3 min group (+6 Gz), and +10 Gz/3 min group (+10 Gz). The changes of learning in rats were measured at 0 d(after +Gz exposure immediately), 2 d, 4 d and 6 d after different +Gz exposure. RESULTS: In Yª²maze test£¬the right number decreased significantly (P<0.01)£¬and time of reaction increased significantly (P<0.01) in +6 Gz and +10 Gz group compared to that in control group; the right number increased significantly in +6 Gz group compared to +10 Gz group (P<0.05). In stepª²through test, latent time at 6 d in experimental groups shortened significantly compared to control group (P<0.01). CONCLUSION: It is suggested that +Gz exposure could impair learning ability of rats extendedly, and increased G level could deteriorate this effect. ......