益肾活血胶囊对肾性贫血大鼠血浆红细胞生成素的影响
益肾活血胶囊,,益肾活血胶囊;慢性肾性贫血;肾功能;促红细胞生成素,0引言,1材料和方法,2结果,3讨论,【参考文献】
Effects of YiShenHuoXue Capsule on erythropoietin in rats with chronic renal anemiaSUN WanSen, WU XiLi, QIAO ChengLin, CUI DaJiang
Department of Integrated Chinese and Western Medicine, Second Hospital, Xi’an Jiaotong University, Xi’an 710004, China
【Abstact】 AIM: To investigate the effects of YiShenHuoXue Capsule (YSWX) on erythropoietin and renal function in rats with chronic renal anemia. METHODS: The rat models of chronic renal anemia were established with adenine (n=30) and then were treated with YSWX. RESULTS: YSWX significantly improved the rats' renal function (BUN mmol/L: 17.5±3.6 vs 28.5±10.6, P﹤0.01; 12.2±3.2 vs 28.5±10.6, P﹤0.01; SCr μmol/L:109.1±10.2 vs 72.1±7.6, P﹤0.01; 93.9±11.7 vs 72.1±7.6, P﹤0.01) and increased the erythropoietin level in plasma (CFUE;11.5±3.4 vs 6.58±2.1, P﹤0.01; 13.2±3.6 vs 6.58±2.1, P﹤0.01). CONCLUSION: YSWX can improve rat renal function and increase erythropoietin level in plasma. ......
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