Effects of infrasound on ultraª²structure of rat myocardium

    PEI Zhaoª²Hui, ZHU Miaoª²Zhang, CHEN Jingª²Zao, ZHANG Yang, PEI Jianª²Ming, ZHUANG Zhiª²Qiang

    1Deparment of Physiology, School of Basic Medicine, 2Infrasound Lab, School of Preventive Medicine, 3Department of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi¡¯an 710033, China

    ¡¾Abstract¡¿ AIM: To observe the ultraª²structure changes of rat myocardium after infrasound exposure. METHODS: One hundred male Spragueª²Dawley rats were randomly divided into 10 groups(n=10): five control groups and five infrasound exposure groups. The rats of the five infrasound exposure groups were exposed 2 h daily to infrasound of 8 Hz, 130 dB for 1, 7, 14, 21 and 28 d, and the ultraª²structures of rat myocardium were observed by transmission electron microscope. RESULTS: The ultraª²structure changes of myocardium in the infrasound exposure groups were: Nearly normal myocardium cells at 1 d, little swelled mitochondia at 7 d, more swelled mitochondia at 14 d, platelets aggregation seen in the myocardium at 21 d, and bleeding observed in the myocardium at 28 d. Damage of ultraª²structure of myocardium increased gradually from 1 d to 28 d. CONCLUSION: Infrasound can damage the ultraª²structure of myocardium, which is related to the infrasound exposure time. ......