Clinical comparison of mild hypothermia beatingª²heart and moderate hypothermia arrestedª²heart intracardiac procedure in pediatrics

    CHENG Wei£¬XIAO Yingª²Bin£¬CHEN Lin£¬ZHONG Qianª²Jin£¬WANG Xueª²Feng£¬CHEN Baiª²Cheng£¬CHEN Jinª²Jin

    Department of Cardiovascular Surgery£¬Xinqiao Hospital£¬Third Military Medical Univesity£¬Chongqing 400037£¬China

    ¡¾Abstract¡¿ AIM: To compare the effects of mild hypothermia beatingª²heart cardiopulmonary bypass (CPB) with those of moderate hypothermia arrestedª²heart CPB in pediatric intracardiac procedure. METHODS: 518 patients whose age were under 3 years underwent open heart surgery. In group 1, 96 patients underwent arrestedª²heart operation, and in group 2, 422 patients underwent beatingª²heart operations. Duration of CPB, incidence of low cardiac output and postoperative concentration of creatine kinase myocardial band(CKª²MB), ect, were compared between the two groups. RESULTS: Duration of CPB and postoperative mechanical respiratory assistance duration in group 2 were shorter than those in group 1 (P<0.01). Transfusion requirements and blood loss were fewer in group 2 than those were in group 1 (P<0.01) . The incidence of low cardiac output syndrome was lower in group 2 (P<0.05). Concentration of CKª²MB and percentage of metabolism acidosis were lower in group 2 than those were in group 1 (P<0.01), while the index of oxygenation was higher in group 2 (P<0.01). CONCLUSION: The effect of mild hypothermia beatingª²heart CPB is superior to that of moderate hypothermia arrestedª²heart CPB in pediatric cardiac surgery. Therefore, the mild hypothermia beatingª²heart CPB is a safe and effective technique applied to pediatric cardiac surgery. ......