Study of airborne insect allergen in asthmatic patients

    SUN Xiuª²Zhen, LIU Yun, LI Yaª²Li, ZHOU Ding

    Department of Respiratory Medicine, Second Hospital, Xi¡¯an Jiaotong University£¬ Xi¡¯an 710004, China

    ¡¾Abstract¡¿ AIM: To study the variety of airborne allergic insects and its irritability in asthmatic patients in Xi¡¯an area and to provide experimental gist for etiological study and prevention of asthma. METHODS: Three hundred asthmatic patients and 100 normal controls underwent skin prick test (SPT) with 13 kinds of superior airborne insect vaccine, and sera sIgE of those with positive SPT results were tested by BSAª²ELISA. RESULTS: The positivity rate of SPT with the 13 kinds of insect vaccine in asthmatic patients was 60%, significantly higher than that in normal controls (P<0.01). The positivity rate of SPT with Stayridae, Heliothis armigera, Psilgramma menephorn and other 7 kinds of insects were more than 30% in asthmatic patients, indicating that these 10 kinds of insects were the main allergic insects in asthmatic patients. The positivity rate of sIgE in asthmatic patients was more than 85%, significantly higher than that in normal control¡¯s (6%, P<0.01). CONCLUSION: Stayridae, Heliothis armigera, Psilgramma menephorn and other 7 kinds of insects may be the main allergic insects in asthmatic patients in Xi¡¯an area and maybe be the main allergens to the onset of asthma in the end summer and the early autumn. ......