心力衰竭__(期刊论文)

充血性心衰患者血浆内皮素，降钙素基因相关肽和神经肽的变化

http://www.100md.com 《第四军医大学学报》 2003年第6期

心力衰竭,,心力衰竭，充血性；内皮缩血管肽类；降钙素基因相关肽；神经肽Y,0引言,1对象和方法,2结果,3讨论,【参考文献】

     (西安市中心医院心血管内科, 陕西西安710003)

    Plasma endothelin,calcitonin gene relative peptide and neuropeptide Y in patients with congestive heart failure

    XIN WeiChuan, FENG GuanLi,BAI YinZhu

    Department of Cardiovasology, Xi’an Central Hospital, Xian 710003, China

    【Abstract】 AIM:To study the changes of plasma endothelin (ET),calcitonin gene relative peptide (CGRP) and neuropeptide Y (NPY) in patients with congestive heart failure and their clinical significance. METHODS: There were 42 patients (male 31,female 11, age 47±12 years old) with congestive heart failure including cor pulmonale(n=10),rheumatic heart disease(n=19) and dilated cardiomyopathy(n=13), and cardiac function (NYHA grade) consisted of Ⅱ(n=14), Ⅲ(n=23) and Ⅳgrade (n=5). With routine therapy for the patients, plasma levels of ET, CGRP, NPY were determinated by radioimmunossay kit at fasting 07:00 AM in second hospitalization day and 4 weeks after therapy.RESULTS: After internal medical therapy for 4 weeks, there were effects and cardiac function improvment toⅠ(n=9),Ⅱ(n=28),Ⅲ(n=4) and Ⅳgrade (n=1); and in contrast with pretherapy, plasma (μg·L-1)ET(112±28 vs 74±15 ......

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