诺迪康胶囊_____诺迪康胶囊；过氧化脂质；电镜；线粒体

诺迪康胶囊对衰老小鼠脑过氧化脂质及线粒体超微结构的影响

http://www.100md.com 《第四军医大学学报》 2003年第7期

诺迪康胶囊,,诺迪康胶囊；过氧化脂质；电镜；线粒体

     (第四军医大学西京医院神经内科，陕西西安 710033)

    Effects of NuoDiKang Capsule on lipidperoxide and mitochondria ultrastructure in the brain of aging rats

    ZHANG ZhiJun, JIANG Wen, WAN Qun

    Department of Neurology, Xijing Hospital, Fourth Military Medical University, Xian 710033，China

    【Abstract】 AIM: To study the effects and mechanism of NuoDiKang Capsule (NDKC) on aging delaying. METHODS: Aging rats induced by Dgalactose were treated with NDKC for 8 weeks and then the content of lipidperoxides (LPO), malondialdehyde (MDA), superoxide dismutase(SOD) and lactate dehydrogenase (LDH) was measured in the brain tissues. Ultrastructural changes of neuron mitochondria were viewed under transmission electron microscope. RESULTS: NDKC markedly decreased the content of LPO and MDA and increased the activity of SOD and LDH in the brain tissues of aging rats at the dose of 1, 2, 4 g·kg-1. At the dose of 2, 4 g·kg-1, NDKC had marked protective effects on mitochondria ultrastructure. CONCLUSION: NDKC has marked aging delaying effects due to its free radical scavenging activity and neural protection. ......

百拇医药网 http://www.100md.com/html/DirDu/2006/02/19/87/26/29.htm

您现在查看是摘要页，全文长 7363 字符。