Comparison of patientª²controlled epidural bolus administration of chloroprocaine and ropivacaine for analgesia during labor

    GONG Hui, YAN Jianª²Jun, LI Gongª²She, ZHANG Ping, ZAI Miaoª²Qin

    Department of Aneasthesia, Maternity and Child Health Care Hospital, Xi¡¯an 710003, Shaanxi Province, China

    ¡¾Abstract¡¿ AIM: To compare the effects of epidural 10 g/L chloroprocaine and 1.25 g/L ropivacaine by patientª²controlled epidural analgesia (PCEA) in labour. METHODS: Fortyª²eight ASA I or II first time lyingª²in women requesting epidural analgesia in early labor were allocated to receive either 10 g/L chloroprocaine with 0.03 g/L fentanyl or 1.25 g/L ropivacaine with 0.03 g/L fentanyl via a patientª²controlled analgesia pump. The pump was stopped at the beginning of the second stage of labor. Visual Analgesia Scores (VAS) and Modified Bromage Score (MBS) were estimated and recorded at four time points: Before analgesia, 5 min after epidural loading dose, 30 min after epidural loading dose, and beginning of the second stage of labor. Duration of labor and Apgar scores at 1min and 5 min after parturition were also compared. RESULTS: There was a significant difference in VAS at 5min after epidural loading dose between the two groups and no difference was observed at other time points. MBS, duration of labor, and Apgar scores were similar in the two groups. CONCLUSION: A 10 g/L chloroprocaine and 1.25 g/L ropivacaine are clinically of similar effects in labor analgesia. ......