大黄对危重症患者胃肠功能衰竭的防治作用.PDF
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2006年2月23日
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大黄对危重症患者胃肠功能衰竭的防治作用
袁正强 陈微微 张 历 温建立 曹建林 贵州省遵义医院 ICU 室 遵义 563002
摘 要 目的: 研究大黄对危重症患者胃肠功能衰竭的防治作用。方法: 将严重创伤、感染性休克、重症胰腺炎等危重症患者随机分为大黄预防组和非大黄预防组, 将非大黄预防组中出现的应激性
胃肠粘膜病变和中毒性肠麻痹患者作为大黄治疗组的研究对象。观察预防组和非预防组患者胃肠
道并发症的发生率。结果: 大黄预防组患者应激性胃肠粘膜病变、中毒性肠麻痹的发生率明显低于
非预防组, 大黄对应激性胃肠粘膜病变的有效率 7718% , 中毒性肠麻痹的缓解率 75%。结论: 大黄
能预防和治疗危重症患者胃肠功能衰竭。
关键词 胃肠功能衰竭 危重症 大 黄 防 治
The Preven t ion and treatmen t Ef fect of Rhubarb on Gastro in test inal Funct ion Fa ilure in Cr it ical Pat ien ts YUAN
Zhengqiang, et al . Z uny i H osp ital in P rov ince, Gu iz ho Z uny i (563002) Ch ina
Abstract Object ive: To study the p revent ion and t reatment effect of rhubarb on gast ro intest inal funct ion failure
in cr it ical Illness . Methods : A ll cr it ical pat ients including cr it ical wound, infect ion shock and cr it ical pancreat it is
w ere random ly dividedly into rhubarb p revent ion group (RPG) and non2rhubarb p revent ion group (NRPG). Tho se
pat ients w ith st ress gast ro intest inal muco sit is o r po isoning intest ine lull in NRHG w ere taken as study object in
RPG The occur rence rat io s w ere observed in bo th group s . Results : The occur rence rat io of st ress gast ro intest inal
muco sit is o r po isoning intest ine lull in RPG w as low er than that in NRPG signif icant ly . The effect ive rat io of
rhubarb on st ress gast ro intest inalmuco sit isw as 77. 80, and the relieve rat io of rhubarb on po isoning intest ine lull
w as 75%. Conclus ion: Rhubarb can p revent and t reat cr it ical gast ro intest inal funct ion failure .
Key words : rhubarb cr it ical illness gast ro intest inal funct ion failure
危重症患者常发生胃肠功能衰竭, 中药大黄有
活血化瘀、清热解毒等功效, 本研究观察大黄对应激
性胃肠粘膜病变和中毒性肠麻痹的预防作用。
1 临床资料
ICU 室患者 46 例, 男 27 例, 女 19 例, 年龄 20
～76 岁, 平均5814 岁 ......
袁正强 陈微微 张 历 温建立 曹建林 贵州省遵义医院 ICU 室 遵义 563002
摘 要 目的: 研究大黄对危重症患者胃肠功能衰竭的防治作用。方法: 将严重创伤、感染性休克、重症胰腺炎等危重症患者随机分为大黄预防组和非大黄预防组, 将非大黄预防组中出现的应激性
胃肠粘膜病变和中毒性肠麻痹患者作为大黄治疗组的研究对象。观察预防组和非预防组患者胃肠
道并发症的发生率。结果: 大黄预防组患者应激性胃肠粘膜病变、中毒性肠麻痹的发生率明显低于
非预防组, 大黄对应激性胃肠粘膜病变的有效率 7718% , 中毒性肠麻痹的缓解率 75%。结论: 大黄
能预防和治疗危重症患者胃肠功能衰竭。
关键词 胃肠功能衰竭 危重症 大 黄 防 治
The Preven t ion and treatmen t Ef fect of Rhubarb on Gastro in test inal Funct ion Fa ilure in Cr it ical Pat ien ts YUAN
Zhengqiang, et al . Z uny i H osp ital in P rov ince, Gu iz ho Z uny i (563002) Ch ina
Abstract Object ive: To study the p revent ion and t reatment effect of rhubarb on gast ro intest inal funct ion failure
in cr it ical Illness . Methods : A ll cr it ical pat ients including cr it ical wound, infect ion shock and cr it ical pancreat it is
w ere random ly dividedly into rhubarb p revent ion group (RPG) and non2rhubarb p revent ion group (NRPG). Tho se
pat ients w ith st ress gast ro intest inal muco sit is o r po isoning intest ine lull in NRHG w ere taken as study object in
RPG The occur rence rat io s w ere observed in bo th group s . Results : The occur rence rat io of st ress gast ro intest inal
muco sit is o r po isoning intest ine lull in RPG w as low er than that in NRPG signif icant ly . The effect ive rat io of
rhubarb on st ress gast ro intest inalmuco sit isw as 77. 80, and the relieve rat io of rhubarb on po isoning intest ine lull
w as 75%. Conclus ion: Rhubarb can p revent and t reat cr it ical gast ro intest inal funct ion failure .
Key words : rhubarb cr it ical illness gast ro intest inal funct ion failure
危重症患者常发生胃肠功能衰竭, 中药大黄有
活血化瘀、清热解毒等功效, 本研究观察大黄对应激
性胃肠粘膜病变和中毒性肠麻痹的预防作用。
1 临床资料
ICU 室患者 46 例, 男 27 例, 女 19 例, 年龄 20
～76 岁, 平均5814 岁 ......
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