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编号:11123991
肝硬化红细胞钠钾ATP酶、钙镁ATP酶及钠钾钙镁改变
http://www.100md.com 王方剑, 刘安立, 曹 洁, 卢永宏, 赵青娥,
关键词:肝硬化;红细胞;Na+-K+-ATP酶;Ca2+-Mg2+-ATP酶,王方剑,刘安立,卢永宏,赵青娥,韩升祥,曹洁,蒙玲,通讯作者:,Cha
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     王方剑, 刘安立, 卢永宏, 赵青娥, 韩升祥,天津解放军第464医院内二科 天津市南开区 300381

    曹洁, 天津解放军第464医院特诊科 天津市南开区 300381

    蒙玲, 93735部队进修生

    通讯作者: 王方剑, 300381, 天津市南开区李七庄, 解放军第464医院内二科. 49269356@51uc.com

    电话: 022-23383929 

    收稿日期: 2005-12-12 接受日期: 2005-12-31

    Changes of activities of erythrocyte membrane Na+-K+-ATPase and Ca2+-Mg2+-ATPase and concentrations of Na+, K+, Ca2+ and Mg2+ in erythrocytes of patients with liver cirrhosis

    Fang-Jian Wang, An-Li Liu, Jie Cao, Yong-Hong Lu, Qing-E Zhao, Sheng-Xiang Han, Ling Meng

    Fang-Jian Wang, An-Li Liu, Yong-Hong Lu, Qing-E Zhao, Sheng-Xiang Han, the Second Department of Internal Medicine, the 464th Hospital of Chinese PLA, Tianjin 300381, China

    Jie Cao, Department of Ultrasonic Diagnosis, the 464th Hospital of Chinese PLA, Tianjin 300381, China

    Ling Meng, Advanced Student from Troop 93735 of Chinese PLA

    Correspondence to: Fang-Jian Wang, the Second Department of Internal Medicine, the 464th Hospital of Chinese PLA, Nankai District, Tianjin 300381,China. 49269356@51uc.com

    Received: 2005-12-12 Accepted: 2005-12-31

    Abstract

    AIM: To probe the activity changes of erythro-cyte membrane Na+-K+-ATPase (NKA) and Ca2+-Mg2+-ATPase (CMA) and their effects on the concentrations of intracellular sodium, potassi-um, calcium and magnesium in patients with liver cirrhosis.

    METHODS: The erythrocyte membrane NKA and CMA activities, and the erythrocyte and serum sodium, potassium, calcium and magnesium (RNa, RK, RCa, RMg; SNa, SK, SCa, SMg) concentrations were measured in 52 patients with decompensated cirrhosis (group A), 36 patients with compensated cirrhosis (group B) and 36 healthy individuals (controls).

    RESULTS: Compared with those in control group, the activities of NKA, CMA and the concentrations of RK and RMg in both group A (t = 5 ......

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