喉肿瘤_____肿瘤；细胞；青蒿素；喉肿瘤

双氢青蒿素对人喉癌细胞HeP2生长抑制作用的实验观察

http://www.100md.com 《第四军医大学学报》 2004年第24期

喉肿瘤,,肿瘤；细胞；青蒿素；喉肿瘤,0引言,1材料和方法,2结果,3讨论,【参考文献】

     Inhibitory effect of pair of hydrogen artemisinin on HeP2 cells of throat cancer

    MENG Yu, LI Yan, LIU Bin, WU JunZheng

    1Brigade of Cadets, 2Department of Oral Biology, Qindu Stomatological College, Fourth Military Medical University, Xian 710033, China

    【Abstract】AIM： To observe the growth inhibitory effects of pair of hydrogen artemisinin on HeP2 cells of throat cancer. METHODS: Cell proliferation was studied by MTT assay and soft agar cloning test. Different concentrations of pair of hydrogen artemisinin were applied, and IC50 and the cloning ratio of the drug against the cells were calculated. RESULTS: Pair of hydrogen artemisinin inhibited the proliferation of Hep2 in a time and dose dependent manner. The IC50 of the drug against the cells was 4466.84 μg/L, and the cloning ratio (%) of the cells exposed to the drug at 320, 1000, 3200 and 10000 μg/L was 1150%, 09%, 06%and 05% respectively, while that of the control was 12. CONCLUSION: Pair of hydrogen artemisinin inhibits the growth of Hep2 cells. ......

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