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霍奇金淋巴瘤CD99基因表达缺失的意义
http://www.100md.com 《第四军医大学学报》 2004年第23期
霍奇金淋巴瘤,,霍奇金淋巴瘤;,免疫组织化学;,CD99基因,0引言,1材料和方法,2结果,3讨论,【参考文献】
     Expression of CD99 in classical hodgkin’s lymphoma

    LI XianMao, LI Yan,ZHAO Tong, ZHU MeiGang,ZHANG JingHua

    1Department of Pathology, Southern Medical University, Guangzhou,510515, 2The 6th Department of Internal Medicine, People’s Hospital, Tibetan Autonomous Region, Lasa 850000, China

    【Abstract】 AIM: To study the expression of CD99 of ReedSternberg cells in classical Hodgkin’s lymphoma (cHL). METHODS: Eight cHL cases were confirmed according to the new WHO pathological classification. Immunohistochemistry for CD99 was performed with SABC method, and the CD99 expression of cell lines was tested by flow cytometer. RESULTS: The positive expression of CD99 was 0% (0/8). The CD99 expression of DG75 and Jurkat cell lines was (87.3±0.4)% and (96.8±0.6)%, and the CD99 expression of L428 cell line was (3.8±0.4)%. The CD99 expression of HDLM2 cell line was (66.4±0.3)%. CONCLUSION: Downexpression of CD99 in HRS cells may be a useful index for the diagnosis of classical Hodgkin’s lymohoma. ......

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