急性肝炎患者系列血清分型及发病特征研究
肝炎,,肝炎,病毒性;血清分型;流行病学,1材料与方法,2结果与分析,3讨论,【参考文献】
【摘要】 目的 通过系列血清的检测来明确肝炎诊断,区分肝炎型别并比较其发病特征,为病毒性肝炎的监测和防治提供科学依据。 方法 应用ELISA法对60例无慢性肝病史的急性肝炎住院患者的166份系列血清进行甲、乙、丙、戊型肝炎病毒的血清标志物的检测,并比较不同肝炎的发病特征。 结果 在这60例急性肝炎患者中,乙型肝炎(乙肝)占46.67%,戊型肝炎(戊肝)占21.67%,未分型肝炎占25%,甲型肝炎(甲肝)合并戊肝占1.67%,乙肝合并戊肝占5.00%,丙型肝炎(丙肝)未检出。乙肝及戊肝均以男性为主,乙肝以50岁以下者居多,戊肝则以中老年为主;戊肝的黄疸表现尤其明显。两者的谷丙转氨酶水平随入院时间延长呈对数线性下降,戊肝下降更为明显。 结论 无慢性肝病史的急性肝炎以乙肝及戊肝为主,未分型肝炎仍占较大比重;系列血清可以反映疾病发展过程中相关指标的动态变化,可以更为准确地进行分型诊断。【关键词】 肝炎,病毒性;血清分型;流行病学
Study on serial-sera classification and clinical characteristics of acute hepatitis patients WANG Na ,ZHENG Ying-jie ,JIANG Qing-wu ,TAN Yi-yun,SHEN Hui-guo,GAO Mei-yang ,WANG Yu-chao .
1.Department of Epidemiology,School of Public Health,Fudan University,Shanghai 200032,China;2.Center for Disease Control and Prevention of Minhang District,Shanghai 201100,China
【Abstract】 Objective Serial-sera classification of the inpatients with acute hepatitis were undertaken to confirm the diagnosis,and clinical characteristics of different types of acute hepatitis were compared in order to provide scientific evidence for the surveillance and control of viral hepatitis.Methods ELISA kits were used to detect immunological markers of hepatitis virus A ......
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