Genetic polymorphisms of 5 Y chromosomal STRs loci and haplotypes in Hui ethnic group

    ZHU Boª²Feng, Zhang Feiª²Xiong, LIU Xiª²She, LU Guiª²Ping, QIAN Guangª²Li, ZHU Jiu5, LIU Yao

    1Key Laboratory of Environment and Genes Related to Diseases Xi¬ðan Jiaotong University, Ministry of Education, Xi¬ðan 710061, China, 2Department of Gastroenterology, Affiliated Hospital of Ningxia Medical Collge, Yinchuan 750004, China, 3Forensic Medical Identification Center of Shandong Public Security Bureau, Jinan 255000, China, 4Mile Public Security Bureau, Mile, 652300, Chian, 5Institute of Forensic Science, Ministry of Public Security, Beijing, 100038, Ghina

    ¡¾Abstract¡¿ AIM: To study genetic polymorphisms of 5 Y chromosomal STRs in Hui ethnic group living in Ningxia Hui ethnic autonomous region, in order to evaluate their usefulness in forensic science and enrich the Chinese genetic information resources. METHODS: We investigated 101 unrelated, healthy, male individuals of Hui ethnic group and studied their allelic frequency distributions and haplotype diversity of 5 Y chromosomal STRs. Primer for each loci was labeled with the fluorescence, such as FAM (blue), HEX (green) or TAMRA (yellow). The data of Hui ethnic group were generated through coª²amplification, GeneScan, genotyping, and genetic distribution analysis. RESULTS: Twentyª²nine alleles were detected, with frequencies ranging from 0.0099ª²0.5446. Out of a total of 101 individuals, 94 showed different haplotypes, 87 were unique, and 7 were found 2 times. The haplotype diversity for 5 Yª²STR loci was 0.9986. CONCLUSIONS: The date can be well useful for individual identification, paternity testing in forensic fields and for population genetics because of 5 Yª²STR high genetic polymorphism. ......