Clinical application of transferring cryopreserved human embryos

    WANG Xiaoª²Hong, LUO Yaª²Ning, LI Li, YANG Yanª²Hong, YAN Kaiª²Lin, HUANG Jianª²Lei, MIN Baoª²Hua

    Department of Obstetrics and Gynecology, Tangdu Hospital, Fourth Military Medical University, Xi¬ðan 710038, China

    ¡¾Abstract¡¿ AIM: To study the clinical application of transferring frozenª²thawed embryos and to analyze the factors influencing the outcome of frozenª²thawed embryos transfer (FET). METHODS: Eighty FET cycles in 63 cases from September 2003 to December 2004 were analyzed retrospectively. The suppernumberary embryos obtained from in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) were cryopreserved by slow freezing and rapid thawing method. RESULTS: Two hundred and sixtyª²nine out of the 392 thawed embryos survived, with an embryo survival rate of 68.62%. The pregnancy rate was 23.75% per FET cycle. The pregnancy rate was significantly higher in the group of transferring 3 embryos than that of transferring ¡Ü2 embryos(30.91% vs 8%, P<0.05). There was significant difference between the conceived and nonconceived cycles in term of the rate of cleavage integrality and the percentage of quality embryos (67.28% vs 60.09%, 89.09% vs 73.55%, respectively P<0.025). CONCLUSIONS: The number and quality of frozenª²thawed embryos transferred are the most important factors influencing the pregnancy rate after frozenª²thawed embryo transfer. ......